ACCUEIL

Consignes aux
auteurs et coordonnateurs
Nos règles d'éthique
Autres revues >>

Sciences des Aliments

0240-8813
parution suspendue
An international journal of food science and technology
 

 ARTICLE VOL 22/4 - 2002  - pp.371-380  - doi:10.3166/sda.22.371-380
TITLE
Conjugated linoleic acid isomers (CLA): good for everything?

ABSTRACT

Evidence of causal link between food and nutrition and some diseases such as cancer, atherosclerosis and diabetes is often sufficiently strong to be a basis for recommendation to prevent them. Polyunsaturated fatty acids in general have always been claimed to modulate the pathogenesis of these diseases. In fact, dietary fatty acids are indeed able to drive lipid metabolism by affecting gene expression (JUMP and CLARKE, 1999). Milk fatty acids had always had a bad literature for its relative high content of some saturated fatty acids which may increase plasma cholesterol associated to LDL. However, recently much attention has been directed toward an unusual fatty acid, conjugated linoleic acid (CLA), which is naturally present in milk, dairy products and ruminant’s meat for the unique ability of rumen bacteria to convert linoleic acid into CLA via an enzymatic isomerase reaction (GRIINARI and BAUMAN, 1999). In this case the main isomer formed is 9cis, 11trans. The formation of CLA is part of an overall process called biohydrogenation that takes place in the rumen, which converts linoleic acid, or less efficiently other 18 Carbon PUFAs with double bonds in 9 and 12 positions, to stearic acid (GRIINARI and BAUMAN, 1999). Furthermore, it has been demonstrated that manipulating cow’s dietary PUFA intake it is possible to modulate milk CLA content (STANTON et al., 1997). Therefore, ruminants are the major reservoir for this fatty acid. During this process vaccenic acid is also formed, which may be converted to CLA in all organisms that possess delta 9 desaturase (CORL et al., 2001). Therefore vaccenic may serve as a precursor of CLA.

AUTEUR(S)
Sebastiano BANNI, Elisabetta MURRU, Elisabetta ANGIONI, Gianfranca CARTA, Maria Paola MELIS

LANGUE DE L'ARTICLE
Anglais

 PRIX
• Abonné (hors accès direct) : 34.95 €
• Non abonné : 34.95 €
|
|
--> Tous les articles sont dans un format PDF protégé par tatouage 
   
ACCÉDER A L'ARTICLE COMPLET  (119 Ko)



Mot de passe oublié ?

ABONNEZ-VOUS !

CONTACTS
Comité de
rédaction
Conditions
générales de vente

 English version >> 
Lavoisier